IL-37 antibody

Catalog No. ABIN5705292

This anti-IL-37 antibody is a Rabbit Polyclonal antibody detecting IL-37 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for IL-37 antibody (ABIN5705292)

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-37 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL-37 Antibody

Purpose: IL37 antibody

Immunogen: interleukin 1 family, member 7 (zeta)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IL-37

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Alternative Name: IL37

Background:

Synonyms: Interleukin-37 (IL-37)|FIL1 zeta|IL-1X|Interleukin-1 family member 7 (IL-1F7)|Interleukin-1 homolog 4 (IL-1H, IL-1H4)|Interleukin-1 zeta (IL-1 zeta)|Interleukin-1-related protein (IL-1RP1)|IL37|FIL1Z|IL1F7|IL1H4|IL1RP1

Background: Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

Gene ID: 27178

UniProt: Q9NZH6