TSG101 antibody
Quick Overview for TSG101 antibody (ABIN5706095)
Target
See all TSG101 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- tumor susceptibility gene 101
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Isotype
- IgG
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Application Notes
- WB:1:200-1:2000,IP:1:200-1:2000,IHC:1:100-1:500,IF:1:10-1:100
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Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09040(TSG101 antibody) at dilution of 1:500
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Expiry Date
- 12 months
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Alternative Name
- TSG101
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Background
- Synonyms:ESCRT I complex subunit TSG101, TSG10, TSG101, tumor susceptibility gene 101, VPS23 Background:The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
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Molecular Weight
- 46kDa
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Gene ID
- 7251
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UniProt
- Q99816
Target
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