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TSG101 antibody

The Rabbit Polyclonal anti-TSG101 antibody has been validated for WB, IHC, ELISA, IP, IF and FACS. It is suitable to detect TSG101 in samples from Human, Mouse and Rat.
Catalog No. ABIN5706095

Quick Overview for TSG101 antibody (ABIN5706095)

Target

See all TSG101 Antibodies
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivity

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Human, Mouse, Rat

Host

  • 67
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Rabbit

Clonality

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Polyclonal

Conjugate

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  • 2
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This TSG101 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
  • Immunogen

    tumor susceptibility gene 101

    Isotype

    IgG
  • Application Notes

    WB:1:200-1:2000,IP:1:200-1:2000,IHC:1:100-1:500,IF:1:10-1:100

    Comment

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab09040(TSG101 antibody) at dilution of 1:500

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze / thaw cycles.

    Storage

    -20 °C

    Expiry Date

    12 months
  • Target

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    Alternative Name

    TSG101

    Background

    Synonyms:ESCRT I complex subunit TSG101, TSG10, TSG101, tumor susceptibility gene 101, VPS23 Background:The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

    Molecular Weight

    46kDa

    Gene ID

    7251

    UniProt

    Q99816
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