CDKAL1 antibody (Internal Region)

Catalog No. ABIN570672

This anti-CDKAL1 antibody is a Goat Polyclonal antibody detecting CDKAL1 in WB and ELISA. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for CDKAL1 antibody (Internal Region) (ABIN570672)

Target: CDKAL1 (CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CDKAL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-CDKAL1 Antibody

Binding Specificity: Internal Region

Purpose: CDKAL1

Sequence: QVKKQRTKDL SR

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-QVKKQRTKDLSR, from the internal region of the protein sequence according to NP_060244.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: This antibody has been described in a publication and it has been successfully used on Human islets and pancreatic insulinoma INS-1 and MIN6 cells . Preliminary experiments gave an approx. 39 kDa band in Human Brain (Cerebellum) lysates afte

Peptide ELISA: antibody detection limit dilution 1:64000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-CDKAL1 antibody (ABIN570672)

Brambillasca, Altkrueger, Colombo, Friederich, Eickelmann, Mark, Borgese, Solimena: "CDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a tail-anchored protein in the endoplasmic reticulum (ER) of insulinoma cells." in: The Journal of biological chemistry, Vol. 287, Issue 50, pp. 41808-19, (2012) (PubMed).

Target Details for CDKAL1

Target: CDKAL1 (CDK5 Regulatory Subunit Associated Protein 1-Like 1 (CDKAL1))

Alternative Name: CDKAL1

Background: CDK5 regulatory subunit associated protein 1-like 1 , FLJ20342, FLJ46705, MGC75469

Gene ID: 54901, 68916, 361243

NCBI Accession: NP_060244