Cytokeratin 19 antibody

Catalog No. ABIN5707735

This anti-Cytokeratin 19 antibody is a Rabbit Monoclonal antibody detecting Cytokeratin 19 in IHC (p). Suitable for Human.

Quick Overview for Cytokeratin 19 antibody (ABIN5707735)

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cytokeratin 19 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT19-1959R

Product Details anti-Cytokeratin 19 Antibody

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: Human mammary epithelial organoids were used as the immunogen for the recombinant KRT19 antibody.

Isotype: IgG kappa

Application Details

Application Notes: Optimal dilution of the recombinant KRT19 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant KRT19 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Cytokeratin 19

Target: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Alternative Name: KRT19 / Cytokeratin 19

Background: Recognizes a protein of 40  kDa, identified as cytokeratin-19 (CK19), which is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50 % -60 % of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.