KRT16 antibody (C-Term)

Catalog No. ABIN5707759

This anti-KRT16 antibody is a Rabbit Monoclonal antibody detecting KRT16 in IHC (p). Suitable for Human.

Quick Overview for KRT16 antibody (C-Term) (ABIN5707759)

Target: KRT16 (Keratin 16 (KRT16))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KRT16 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT16-2043R

Product Details anti-KRT16 Antibody

Binding Specificity: C-Term

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: A C-terminal region peptide was used as the immunogen for the recombinant Keratin 16 antibody.

Isotype: IgG kappa

Application Details

Application Notes: Optimal dilution of the recombinant Keratin 16 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Keratin 16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for KRT16

Target: KRT16 (Keratin 16 (KRT16))

Alternative Name: KRT16 / Cytokeratin 16

Background: Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.