FTL antibody (AA 38-165)

Catalog No. ABIN5708056

This anti-FTL antibody is a Rabbit Monoclonal antibody detecting FTL in IHC (p). Suitable for Human.

Quick Overview for FTL antibody (AA 38-165) (ABIN5708056)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FTL antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FTL-2338R

Product Details anti-FTL Antibody

Binding Specificity: AA 38-165

Purification: Purified

Purity: Protein A affinity chromatography

Immunogen: Amino acids 38-165 of human FTL1 were used as the immunogen for this recombinant Ferritin Light Chain antibody.

Isotype: IgG kappa

Application Details

Application Notes: Optimal dilution of the recombinant Ferritin Light Chain antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Ferritin Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: FTL1 / Ferritin light chain

Background: The FTL gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. This gene has multiple pseudogenes.

Although ferritin light chain has no ferroxidase activity, the light chain may be responsible for the electron transfer across the ferritin protein cage. [Wiki]

Pathways: Transition Metal Ion Homeostasis