IL27 antibody (AA 29-234)

Catalog No. ABIN5708088

The Rabbit Polyclonal anti-IL27 antibody has been validated for WB and ELISA. It is suitable to detect IL27 in samples from Mouse and Rat.

Quick Overview for IL27 antibody (AA 29-234) (ABIN5708088)

Target: IL27 (Interleukin-27 Subunit alpha (IL27))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL27 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL27 Antibody

Binding Specificity: AA 29-234

Purification: Antigen affinity purified

Immunogen: A mouse partial recombinant protein corresponding to amino acids F29-S234 was used as the immunogen for the Il-27 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Il-27 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant mouse protein) (BSA-free format available)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Il-27 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for IL27

Target: IL27 (Interleukin-27 Subunit alpha (IL27))

Alternative Name: Il-27 (alpha subunit)

Background: Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

UniProt: Q8K3I6