GRM2 antibody (C-Term)

Catalog No. ABIN5708176

This anti-GRM2 antibody is a Rabbit Polyclonal antibody detecting GRM2 in WB. Suitable for Human.

Quick Overview for GRM2 antibody (C-Term) (ABIN5708176)

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GRM2 Antibody

Binding Specificity: AA 681-715, C-Term

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 681-715 from human GRM2 was used as the immunogen for the mGluR2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the mGluR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the mGluR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for GRM2

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Alternative Name: Metabotropic Glutamate Receptor 2

Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport