TLN1 antibody (Internal Region)
Quick Overview for TLN1 antibody (Internal Region) (ABIN571042)
Target
See all TLN1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- Internal Region
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Purpose
- Talin 1 / TLN1
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Sequence
- QEALHTQMLT AVQE
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Specificity
- This antibody is not expected to cross-react with the highly similar protein Talin 2.
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Cross-Reactivity
- Cow, Dog, Human, Mouse, Rat
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Purification
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Immunogen
- Peptide with sequence C-QEALHTQMLTAVQE, from the internal region of the protein sequence according to NP_006280.3.
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Isotype
- IgG
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Application Notes
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Western Blot: A >250 kDa band observed in Human Peripheral Mononucleocyte lysates (calculated MW of 270 kDa according to NP_006280.3). Recommended concentration: 1-3 μg/mL. An additional band of unknown identity was also consistently observed at 110 kDa. Thi
Peptide ELISA: antibody detection limit dilution 1:8000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Minimize freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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- TLN1 (Talin 1 (TLN1))
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Alternative Name
- TLN1
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Background
- TLN1, talin 1, ILWEQ, KIAA1027, TLN
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Gene ID
- 7094, 21894, 313494
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NCBI Accession
- NP_006280
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Pathways
- Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
Target
-