Dynamin 3 antibody (pSer774)

Catalog No. ABIN576280

This Sheep Polyclonal antibody specifically detects Dynamin 3 in WB, IHC, IF and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for Dynamin 3 antibody (pSer774) (ABIN576280)

Target: Dynamin 3 (DNM3)

Reactivity: Rat

Host: Sheep

Clonality: Polyclonal

Conjugate: This Dynamin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Dynamin 3 Antibody

Binding Specificity: pSer774

Specificity: Recognizes rat dynamin when phosphorylated at serine 774. Dynamin is a phosphoprotein expressed at nerve terminals, which plays an important role in the regulation of synaptic vesicle endocytosis. Cyclin dependent protein kinase 5 (cdk5) has been shown to phosphorylate serine 774 and 778 in vivo. Dephosphorylation of these residues is essential for endocytosis of synaptic vesicles.

Purification: Purified

Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence within dynamin which includes phosphorylated Ser774. ( pSer774 ).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IF, IHC, IHC-Fr, WB (1:1000)

Usage: Western Blot: LS-C43073 detects a band of approximately 95kD in rat hippocampus lysates.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 0.09 % sodium azide, 0.01 % BSA, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for Dynamin 3

Target: Dynamin 3 (DNM3)

Alternative Name: DNM3 / Dynamin 3

Background: Name/Gene ID: DNM3

Synonyms: DNM3, Dyna III, Dynamin 3, Dynamin family member, Dynamin-3, Dynamin, testicular, KIAA0820, T-dynamin

Gene ID: 26052

Pathways: Toll-Like Receptors Cascades