PKC alpha antibody (AA 661-672)

Catalog No. ABIN576366

The Mouse Monoclonal anti-PKC alpha antibody (ABIN576366) specifically detects PKC alpha in WB, IHC and IHC (fro). The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Monkey and Hamster samples.

Quick Overview for PKC alpha antibody (AA 661-672) (ABIN576366)

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Hamster

Host: Mouse

Clonality: Monoclonal

Conjugate: This PKC alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PKC alpha Antibody

Binding Specificity: AA 661-672

Specificity: Recognizes the alpha isoform of protein kinase C. PKC-alpha is a 672 amino acid enzyme containing a single domain, a domain, 2 and a single domain. Recognizes the sequence PQFVHPILQSAV at the C terminus of PKCalpha.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda (100%) Elephant, Rabbit, Horse, Opossum, Platypus (92%) Bat (83%).

Immunogen: Protein kinase C alpha. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda (100%), Elephant, Rabbit, Horse, Opossum, Platypus (92%), Bat (83%).

Isotype: IgG2a

Application Details

Application Notes: Approved: IHC, IHC-Fr (1:1 - 1:10), WB (1:10 - 1:500)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tissue culture supernatant, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for PKC alpha

Target: PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))

Alternative Name: PRKCA / PKC-alpha

Background: Name/Gene ID: PRKCA
Subfamily: PKC
Family: Protein Kinase

Synonyms: PRKCA, Aging-associated gene 6, AAG6, Alpha PKC, PKC-A, Pkcalpha, Protein kinase C alpha type, PKC Alpha, PKC-alpha, PKCA, Protein kinase c alpha, Protein kinase C, alpha

Gene ID: 5578

Pathways: WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling