VCctxB (Subunit beta) antibody

Catalog No. ABIN576688

This Rabbit Polyclonal antibody specifically detects VCctxB in ELISA and IP. It exhibits reactivity toward Vibrio cholerae.

Quick Overview for VCctxB (Subunit beta) antibody (ABIN576688)

Target: VCctxB

Reactivity: Vibrio cholerae

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunoprecipitation (IP)

Product Details

Binding Specificity: Subunit beta

Specificity: Recognizes the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Purification: Purified

Immunogen: Purified Choleragenoid.

Type of Immunogen: Purified protein

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Vibrio cholerae

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details

Target: VCctxB

Alternative Name: Cholera Toxin B Subunit

Background: Name/Gene ID: VC1456
Family: Virulence Factor

Synonyms: VC1456, VCctxB

Gene ID: 2613962