eIF2 alpha/eif2s1 (AA 1-315) antibody

Catalog No. ABIN5775940

The Mouse Monoclonal anti-eIF2 alpha/eif2s1 antibody is suitable to detect eIF2 alpha/eif2s1 in samples from Human. It has been validated for WB, ELISA, ICC and IF.

Quick Overview for eIF2 alpha/eif2s1 (AA 1-315) antibody (ABIN5775940)

Target: eIF2 alpha/eif2s1

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT5E10

Product Details

Binding Specificity: AA 1-315

Purpose: Human eIF-2 alpha/EIF2S1 antibody

Purification: Purified

Immunogen: Recombinant human EIF2S1 (1-315aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details

Target: eIF2 alpha/eif2s1

Alternative Name: eIF-2 alpha/EIF2S1

Background: Eukaryotic translation initiation factor 2, subunit 1 alpha (EIF2S1) is plays a central role in initiating translation, and provides for a rate-limiting step in protein synthesis. The phosphorylation of alpha-subunit of EIF2S1 effectively prevents formation of the EIF2S1/GTP/Met-tRNAi complex and inhibits global protein synthesis.

NCBI Accession: NP_004085