PPME1 antibody (AA 1-386)

Catalog No. ABIN5775977

This anti-PPME1 antibody is a Mouse Monoclonal antibody detecting PPME1 in WB and ELISA. Suitable for Human.

Quick Overview for PPME1 antibody (AA 1-386) (ABIN5775977)

Target: PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPME1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: AT29G3

Product Details anti-PPME1 Antibody

Binding Specificity: AA 1-386

Purpose: Human PPME1 antibody

Purification: Purified

Immunogen: Recombinant human PPME1 (1-386aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for PPME1

Target: PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))

Alternative Name: PPME1

Background: PPME1, also known protein phosphatase methylesterase-1 (PME1), catalyzes the demethylation and inactivation of protein phosphatase (PP2A), which is a multimeric phosphoserine/ threonine protein phosphatase associated with growth inhibition and cell cycle arrest. It can demethylate PP2A catalytic subunit in vitro and okadaic acid treatment is capable of inhibiting this reaction. It is conserved from yeast to human and contains a motif found in lipases having a catalytic triad activated serine as their active site nucleophile.

NCBI Accession: NP_057231

Pathways: Methionine Biosynthetic Process