PPME1 antibody (AA 1-386)
Quick Overview for PPME1 antibody (AA 1-386) (ABIN5775977)
Target
See all PPME1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-386
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Immunogen
- Recombinant human PPME1 (1-386aa) purified from E. coli
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Isotype
- IgG1 kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))
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Alternative Name
- PPME1
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Background
- PPME1, also known protein phosphatase methylesterase-1 (PME1), catalyzes the demethylation and inactivation of protein phosphatase (PP2A), which is a multimeric phosphoserine/ threonine protein phosphatase associated with growth inhibition and cell cycle arrest. It can demethylate PP2A catalytic subunit in vitro and okadaic acid treatment is capable of inhibiting this reaction. It is conserved from yeast to human and contains a motif found in lipases having a catalytic triad activated serine as their active site nucleophile.
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NCBI Accession
- NP_057231
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Pathways
- Methionine Biosynthetic Process
Target
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