TOLLIP antibody (AA 61-274)
Quick Overview for TOLLIP antibody (AA 61-274) (ABIN5775992)
Target
See all TOLLIP AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 61-274
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Immunogen
- Recombinant human Tollip (61-274aa) purified from E. coli
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Isotype
- IgG2a kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- TOLLIP (Toll Interacting Protein (TOLLIP))
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Alternative Name
- Tollip
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Background
- Toll interacting protein, also known as Tollip, is an inhibitory adaptor protein within the signaling pathway of IL-1 and Toll-like receptors (TLR). The Toll-like receptors are essential transmembrane signaling receptors of the innate immune system that alert the host to the presence of a microbial invader. Tollip recruits IRAk1 to the IL-1 receptor complex and inhibits IRAk1 phosphorylation and kinase activity.
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NCBI Accession
- NP_061882
Target
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