TREM2
Reactivity: Mouse
FACS, LCI
Host: Rabbit
Polyclonal
PE
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Storage
4 °C,-20 °C,-80 °C
Storage Comment
Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Target
TREM2
(Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))
Alternative Name
TREM2
Background
The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. And the TYROBP-TREM2 complex also activates cells in the skeletal system and in the brain and spinal cord (central nervous system).