Adenylosuccinate Lyase antibody (AA 1-484)
Quick Overview for Adenylosuccinate Lyase antibody (AA 1-484) (ABIN5776044)
Target
See all Adenylosuccinate Lyase (ADSL) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-484
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Immunogen
- Recombinant human ADSL(1-484aa) purified from E. coli
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Isotype
- IgG1 kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Adenylosuccinate Lyase (ADSL)
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Alternative Name
- Adenylosuccinate Lyase/ADSL
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Background
- Adenylosuccinate lyase, also known as ADSL, is an enzyme that converts adenylosuccinate to AMP and fumarate as part of the purine nucleotide cycle. Defects in ADSL are the cause of adenylosuccinase deficiency (ADSL deficiency). ADSL deficiency is an autosomal recessive disorder characterized by the accumulation in the body fluids of succinylaminoimidazole-carboxamide riboside (SAICA-riboside) and succinyladenosine (S-Ado).
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NCBI Accession
- NP_000017
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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