NQO2 antibody (AA 1-231)

Catalog No. ABIN5776048

The Mouse Monoclonal anti-NQO2 antibody has been validated for WB, ELISA, IF and ICC. It is suitable to detect NQO2 in samples from Human.

Quick Overview for NQO2 antibody (AA 1-231) (ABIN5776048)

Target: NQO2

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NQO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1E3

Product Details anti-NQO2 Antibody

Binding Specificity: AA 1-231

Purpose: Human NQO2 antibody

Purification: Purified

Immunogen: Recombinant human NQO2 (1-231aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for NQO2

Target: NQO2

Alternative Name: NQO2

Background: Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates. NQO2 is inhibited by flavones such as quercetin. Also benzo (a) pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates. The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm.