Cofilin antibody (AA 1-166)

Catalog No. ABIN5776076

This anti-Cofilin antibody is a Mouse Monoclonal antibody detecting Cofilin in WB, ELISA, IF and ICC. Suitable for Human.

Quick Overview for Cofilin antibody (AA 1-166) (ABIN5776076)

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cofilin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1C1

Product Details anti-Cofilin Antibody

Binding Specificity: AA 1-166

Purpose: Human Cofilin 1/CFL1 antibody

Purification: Purified

Immunogen: Recombinant human Cofilin 1 (1-166aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Cofilin

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Alternative Name: Cofilin 1/CFL1

Background: Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.

NCBI Accession: NP_005498

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events