SGTA antibody (AA 1-313)

Catalog No. ABIN5776127

The Mouse Monoclonal anti-SGTA antibody (Clone AT19E8) (ABIN5776127) specifically detects SGTA in WB, ELISA, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for SGTA antibody (AA 1-313) (ABIN5776127)

Target: SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SGTA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT19E8

Product Details anti-SGTA Antibody

Binding Specificity: AA 1-313

Purpose: Human SGTA antibody

Purification: Purified

Immunogen: Recombinant human SGTA (1-313aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for SGTA

Target: SGTA (Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, alpha (SGTA))

Alternative Name: SGTA

Background: SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protein is believed to function as a component of the androgen receptor (AR) -chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances.

NCBI Accession: NP_003012