DECR1 antibody (AA 35-335)

Catalog No. ABIN5776166

The Mouse Monoclonal anti-DECR1 antibody (Clone AT3B2) (ABIN5776166) specifically detects DECR1 in WB, ELISA, ICC, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for DECR1 antibody (AA 35-335) (ABIN5776166)

Target: DECR1 (2,4-Dienoyl CoA Reductase 1, Mitochondrial (DECR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DECR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: AT3B2

Product Details anti-DECR1 Antibody

Binding Specificity: AA 35-335

Purpose: Human DECR1 antibody

Purification: Purified

Immunogen: Recombinant human DECR1 (35-335aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for DECR1

Target: DECR1 (2,4-Dienoyl CoA Reductase 1, Mitochondrial (DECR1))

Alternative Name: DECR1

Background: DECR1 is a mitochondrial protein that exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. It functions as an auxiliary enzyme of beta-oxidation andt participates in the metabolism of unsaturated fatty enoyl-CoA esters. Specifically, DECR1 uses NADP+ to catalyze the reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA, which can then be used as an intermediate in the Krebs cycle. Additionally, DECR1 is thought to function as a tumor suppressor, possibly downregulating the expression of Neu and slowing the rate of tumorigenesis.

NCBI Accession: NP_001350

Pathways: Monocarboxylic Acid Catabolic Process