Fission 1 antibody (AA 1-122)

Catalog No. ABIN5776187

This anti-Fission 1 antibody is a Mouse Monoclonal antibody detecting Fission 1 in WB, ELISA, IF and ICC. Suitable for Human.

Quick Overview for Fission 1 antibody (AA 1-122) (ABIN5776187)

Target: Fission 1 (FIS1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fission 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT3B7

Product Details anti-Fission 1 Antibody

Binding Specificity: AA 1-122

Immunogen: Recombinant human TTC11 (1-122aa) purified from E. coli.

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: FIS1

Background: TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. This protein can induce cytochrome C release from the mitochondrion to the cytosol, ultimately leading to apoptosis. It is also involved in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission.

NCBI Accession: NP_057152

Pathways: Positive Regulation of Endopeptidase Activity