GMFB antibody (AA 1-142)

Catalog No. ABIN5776194

This Mouse Monoclonal antibody specifically detects GMFB in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for GMFB antibody (AA 1-142) (ABIN5776194)

Target: GMFB (Glia Maturation Factor, beta (GMFB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GMFB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT44D8

Product Details anti-GMFB Antibody

Binding Specificity: AA 1-142

Purpose: Human GMF-beta/GMFB antibody

Purification: Purified

Immunogen: Recombinant human GMFB (1-142aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for GMFB

Target: GMFB (Glia Maturation Factor, beta (GMFB))

Alternative Name: GMF-beta/GMFB

Background: GMFB, also known as GMF, belongs to the GMF subfamily of the larger actin-binding protein ADF family. This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMFB in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMFB expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF.

NCBI Accession: NP_004115