GMFB antibody (AA 21-110)

Catalog No. ABIN1387795

Product Details anti-GMFB Antibody

Target: GMFB (Glia Maturation Factor, beta (GMFB))

Binding Specificity: AA 21-110

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GMFB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GMF beta

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GMFB

Target: GMFB (Glia Maturation Factor, beta (GMFB))

Alternative Name: GMF beta (GMFB Products)

Synonyms: fc25b01 antibody, zgc:56451 antibody, zgc:86831 antibody, wu:fa97c03 antibody, wu:fc25b01 antibody, GMFB antibody, DKFZp459J101 antibody, gmfb antibody, 3110001H22Rik antibody, 3110001O16Rik antibody, AI851627 antibody, C79176 antibody, D14Ertd630e antibody, GMF antibody, gmf-beta antibody, glia maturation factor, beta antibody, glia maturation factor beta antibody, Glia maturation factor beta antibody, glia maturation factor, beta L homeolog antibody, gmfb antibody, GMFB antibody, Gmfb antibody, EDI_093190 antibody, Tsp_04922 antibody, LOC100101176 antibody, gmfb.L antibody

Background:

Synonyms: Glia maturation factor beta, GMF. GMF-beta, GMFB, GMFB_HUMAN.

Background: Glia maturation factor _ (GMF-_) belongs to the GMF subfamily of the larger actin-binding protein ADF family. This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF-_ being produced by the tumor cells.