PARK7/DJ1 antibody (AA 1-189)
Quick Overview for PARK7/DJ1 antibody (AA 1-189) (ABIN5776217)
Target
See all PARK7/DJ1 (PARK7) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-189
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Immunogen
- Recombinant human Park7/DJ-1 (1-189aa) purified from E. coli
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Isotype
- IgG2b kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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Alternative Name
- DJ-1/PARK7
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Background
- Parkinson disease (autosomal recessive, early onset) 7, also known as PARK7/DJ-1, has been shown to interact with EFCAB6 and protein inhibitor of activated STAT2. Defects in PARK7 are the cause of autosomal recessive early-onset Parkinson's disease 7. This protein belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death.
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NCBI Accession
- NP_009193
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
Target
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