RUVBL1 antibody (AA 1-456)

Catalog No. ABIN5776235

The Mouse Monoclonal anti-RUVBL1 antibody (Clone AT1D6) (ABIN5776235) specifically detects RUVBL1 in WB, ELISA, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for RUVBL1 antibody (AA 1-456) (ABIN5776235)

Target: RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUVBL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1D6

Product Details anti-RUVBL1 Antibody

Binding Specificity: AA 1-456

Purpose: Human Pontin/RUVBL1 antibody

Purification: Purified

Immunogen: Recombinant human RuVBL1 (1-456aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for RUVBL1

Target: RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))

Alternative Name: Pontin/RUVBL1

Background: RuVBL1, also known as TIP49A, is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto oncogene mediated growth induction, tumor suppressor mediated growth arrest.

NCBI Accession: NP_003698

Pathways: Telomere Maintenance