PDCL3 antibody (AA 1-239)

Catalog No. ABIN5776244

The Mouse Monoclonal anti-PDCL3 antibody (Clone AT8F9) (ABIN5776244) specifically detects PDCL3 in WB, ELISA, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for PDCL3 antibody (AA 1-239) (ABIN5776244)

Target: PDCL3 (Phosducin-Like 3 (PDCL3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDCL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT8F9

Product Details anti-PDCL3 Antibody

Binding Specificity: AA 1-239

Purpose: Human PDCL3 antibody

Purification: Purified

Immunogen: Recombinant human PDCL3 (1-239aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for PDCL3

Target: PDCL3 (Phosducin-Like 3 (PDCL3))

Alternative Name: PDCL3

Background: PDCL3 (phosducin-like 3), also known as VIAF1 (viral IAP-associated factor 1), VIAF, PHLP3 or HTPHLP, is a widely expressed protein that belongs to the phosducin-like family of proteins. phosducin-like family members associate with the cytosolic chaperonin complex (CCT) and regulate the folding of proteins. Localizing to the cytoplasm, PDCL3 does not appear to play a role in G protein signaling, but participates in the chaperone-assisted folding of proteins, such as beta Tubulin and Actin, that are involved in the regulation of cell cycle progression. More specifically, PDCL3, when associated with CCT, represses the ATPase activity of CCT and ultimately disrupts the folding of the Actin or tubulin substrates.

NCBI Accession: NP_076970