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PDCL3 antibody (AA 1-239)

This anti-PDCL3 antibody is a Mouse Monoclonal antibody detecting PDCL3 in WB, ELISA, IF and ICC. Suitable for Human.
Catalog No. ABIN5776244

Quick Overview for PDCL3 antibody (AA 1-239) (ABIN5776244)

Target

See all PDCL3 Antibodies
PDCL3 (Phosducin-Like 3 (PDCL3))

Reactivity

  • 23
  • 1
  • 1
Human

Host

  • 20
  • 3
Mouse

Clonality

  • 20
  • 3
Monoclonal

Conjugate

  • 10
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
This PDCL3 antibody is un-conjugated

Application

  • 14
  • 13
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone

AT8F9
  • Binding Specificity

    • 13
    • 8
    • 2
    • 1
    • 1
    AA 1-239

    Immunogen

    Recombinant human PDCL3 (1-239aa) purified from E. coli

    Isotype

    IgG1 kappa
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target

    PDCL3 (Phosducin-Like 3 (PDCL3))

    Alternative Name

    PDCL3

    Background

    PDCL3 (phosducin-like 3), also known as VIAF1 (viral IAP-associated factor 1), VIAF, PHLP3 or HTPHLP, is a widely expressed protein that belongs to the phosducin-like family of proteins. phosducin-like family members associate with the cytosolic chaperonin complex (CCT) and regulate the folding of proteins. Localizing to the cytoplasm, PDCL3 does not appear to play a role in G protein signaling, but participates in the chaperone-assisted folding of proteins, such as beta Tubulin and Actin, that are involved in the regulation of cell cycle progression. More specifically, PDCL3, when associated with CCT, represses the ATPase activity of CCT and ultimately disrupts the folding of the Actin or tubulin substrates.

    NCBI Accession

    NP_076970
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