FH antibody (AA 44-510)

Catalog No. ABIN5776268

This anti-FH antibody is a Mouse Monoclonal antibody detecting FH in WB, ELISA, IF, FACS and ICC. Suitable for Human.

Quick Overview for FH antibody (AA 44-510) (ABIN5776268)

Target: FH (Fumarate Hydratase (FH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: AT3F6

Product Details anti-FH Antibody

Binding Specificity: AA 44-510

Immunogen: Recombinant human Fumarase (44-510aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for FH

Target: FH (Fumarate Hydratase (FH))

Alternative Name: Fumarase/FH

Background: Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.

NCBI Accession: NP_000134