HDAC2 antibody (Ser394)

Catalog No. ABIN5956848

The Rabbit Polyclonal anti-HDAC2 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect HDAC2 in samples from Human, Mouse, Rat and Monkey.

Quick Overview for HDAC2 antibody (Ser394) (ABIN5956848)

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HDAC2 Antibody

Binding Specificity: Ser394

Specificity: D10Wsu179e,HD 2,HD2,HDAC 2,Hdac2,HDAC2,Histone deacetylase 2 (HD2),Histone deacetylase 2,OTTHUMP00000017046,OTTHUMP00000227077,OTTHUMP00000227078,RPD3,transcriptional regulator homolog RPD3,YAF1,YY1 associated factor 1,YY1 transcription factor binding protein,Yy1bp

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HDAC2

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Alternative Name: HDAC2

Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.

Molecular Weight: 55kDa

Gene ID: 3066

UniProt: Q92769

Pathways: Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection