Cytokeratin 18 antibody (Ser33)

Catalog No. ABIN5959358

This Rabbit Polyclonal antibody specifically detects Cytokeratin 18 in WB, IF, ELISA, IHC (p) and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Cytokeratin 18 antibody (Ser33) (ABIN5959358)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 18 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Product Details anti-Cytokeratin 18 Antibody

Binding Specificity: Ser33

Specificity: Cell proliferation inducing gene 46 protein,Cell proliferation inducing protein 46,Cell proliferation-inducing gene 46 protein,CK 18,CK-18,CK18,CYK 18,CYK18,Cytokeratin 18,Cytokeratin endo B,Cytokeratin-18,K 18,K18,K1C18,KA18,Keratin 18,Keratin 18,type I,Keratin D,keratin,type I cytoskeletal 18,Keratin-18,Krt18

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human Cytokeratin 18 around the non-phosphorylation site of Ser33.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, IP 1:200-1:500, ELISA 1:40000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Alternative Name: Cytokeratin 18

Background: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Molecular Weight: 48kDa

Gene ID: 3875

UniProt: P05783

Pathways: Apoptosis, Caspase Cascade in Apoptosis