tau antibody (Thr212)

Catalog No. ABIN5959716

The Rabbit Polyclonal anti-tau antibody is suitable to detect tau in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF and IHC (p).

Quick Overview for tau antibody (Thr212) (ABIN5959716)

Target: tau (tau Protein)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-tau Antibody

Binding Specificity: Thr212

Specificity: AI413597,AW045860,DDPAC,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,MAPT,MAPTL,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Microtubule-associated protein tau,MSTD,Mtapt,MTBT1,MTBT2,Neurofibrillary tangle protein,Paired helical filament tau,Paired helical filament-tau,PHF tau,PHF-tau,PPND,PPP1R103,Protein phosphatase 1,regulatory subunit 103,pTau,RNPTAU,TAU,TAU,Tauopathy and respiratory failure,included

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human Tau around the non-phosphorylation site of Thr212.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for tau

Target: tau (tau Protein)

Alternative Name: Tau

Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Molecular Weight: 79kDa

Gene ID: 4137

UniProt: P10636