tau antibody (Thr212)
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- Target See all tau Antibodies
- tau (tau Protein)
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Binding Specificity
- Thr212
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This tau antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- AI413597,AW045860,DDPAC,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,MAPT,MAPTL,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Microtubule-associated protein tau,MSTD,Mtapt,MTBT1,MTBT2,Neurofibrillary tangle protein,Paired helical filament tau,Paired helical filament-tau,PHF tau,PHF-tau,PPND,PPP1R103,Protein phosphatase 1,regulatory subunit 103,pTau,RNPTAU,TAU,TAU,Tauopathy and respiratory failure,included
- Purification
- Affinity purification
- Immunogen
- Synthesized peptide derived from human Tau around the non-phosphorylation site of Thr212.
- Isotype
- IgG
- Top Product
- Discover our top product tau Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- tau (tau Protein)
- Alternative Name
- Tau (tau Products)
- Background
- Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
- Molecular Weight
- 79kDa
- Gene ID
- 4137
- UniProt
- P10636
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