KLF1 antibody (Lys274)

Catalog No. ABIN5960969

This Rabbit Polyclonal antibody specifically detects KLF1 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for KLF1 antibody (Lys274) (ABIN5960969)

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-KLF1 Antibody

Binding Specificity: Lys274

Specificity: CDAN4,EKLF,EKLF PEN,Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor),Erythroid krueppel-like transcription factor,Erythroid Kruppel like factor,Erythroid specific transcription factor EKLF,HBFQTL6,Human erythroid-specific transcription factor EKLF mRNA complete cds,INLU,Klf1,KLF1,Krueppel-like factor 1,Kruppel like factor 1 (erythroid)

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human EKLF around the non-acetylation site of K274.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KLF1

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Alternative Name: EKLF

Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

Molecular Weight: 38kDa

Gene ID: 10661

UniProt: Q13351