ENOS antibody (Ser1177)

Catalog No. ABIN5961400

This anti-ENOS antibody is a Rabbit Polyclonal antibody detecting ENOS in WB, ELISA, IF and IHC (p). Suitable for Human, Rat and Mouse.

Quick Overview for ENOS antibody (Ser1177) (ABIN5961400)

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENOS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ENOS Antibody

Binding Specificity: Ser1177

Specificity: CNOS,Constitutive NOS,EC NOS,EC-NOS,ecNOS,Endothelial nitric oxidase synthase,Endothelial nitric oxide synthase,Endothelial nitric oxide synthase 3,Endothelial NOS,eNOS,Nitric oxide synthase 3 (endothelial cell),Nitric oxide synthase 3,Nitric oxide synthase 3 endothelial cell,Nitric oxide synthase endothelial,Nitric oxide synthase,endothelial,NOS 3,NOS III,NOS type III,NOS3,NOS3,NOSIII

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human NOS3 around the non-phosphorylation site of Ser1177.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ENOS

Target: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Alternative Name: NOS3

Background: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

Molecular Weight: 133kDa

Gene ID: 4846

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling