HDAC1 antibody (Ser421, Ser423)

Catalog No. ABIN601460

The Rabbit Polyclonal anti-HDAC1 antibody is suitable to detect HDAC1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for HDAC1 antibody (Ser421, Ser423) (ABIN601460)

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-HDAC1 Antibody

Binding Specificity: Ser421, Ser423

Specificity: Recognizes human HDAC1 when phosphorylated at serine 421/Ser423. Species cross-reactivity: mouse, rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to human HDAC1 around the phosphorylation site of serine 421/423 (E-F-SP-D- SP -E-E).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (1:4000), IHC (1:50 - 1:100), WB (1:500 - 1:1000)

Usage: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. ELISA: 1:4000. Western Blot: 1:500-1:1000. Immunohistochemistry: 1:50-1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for HDAC1

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Alternative Name: HDAC1

Background: Name/Gene ID: HDAC1
Family: Histone Deacetylase

Synonyms: HDAC1, Histone deacetylase 1, GON-10, HD1, RPD3, RPD3L1

Gene ID: 3065

UniProt: Q13547

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis