LIM Domain Kinase 1 antibody (pThr508)

Catalog No. ABIN601741

This Rabbit Polyclonal antibody specifically detects LIM Domain Kinase 1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Chicken, Horse, Rabbit, Xenopus laevis and Zebrafish (Danio rerio).

Quick Overview for LIM Domain Kinase 1 antibody (pThr508) (ABIN601741)

Target: LIM Domain Kinase 1 (LIMK1)

Reactivity: Human, Mouse, Rat, Dog, Chicken, Horse, Rabbit, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIM Domain Kinase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LIM Domain Kinase 1 Antibody

Binding Specificity: pThr508

Specificity: Recognizes human LIM Domain Kinase 1 when phosphorylated at threonine 508.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to human LIMK1 around the phosphorylation site of threonine 508 (R-Y-TP-V-V).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC (1:50 - 1:100), WB (1:500 - 1:1000)

Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:500-1:1000. Immunohistochemistry: 1:50-1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for LIM Domain Kinase 1

Target: LIM Domain Kinase 1 (LIMK1)

Alternative Name: LIMK1 / LIMK

Background: Name/Gene ID: LIMK1
Subfamily: LIMK
Family: Protein Kinase

Synonyms: LIMK1, LIM domain kinase 1, Lim kinase 1, LIMK-1, LIM kinase, LIMK

Gene ID: 3984

UniProt: P53667

Pathways: Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events