MMP14 antibody (Hinge Region)

Catalog No. ABIN609041

The Rabbit Polyclonal anti-MMP14 antibody has been validated for WB, IHC and IHC (p). It is suitable to detect MMP14 in samples from Human and Rat.

Quick Overview for MMP14 antibody (Hinge Region) (ABIN609041)

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP14 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MMP14 Antibody

Binding Specificity: Hinge Region

Specificity: Recognizes human MT1-MMP. It does not cross react with MMP-1, MMP-2, MMP-8, MMP-9, and MMP-13. Species cross-reactivity: rat. Species sequence homology: mouse, (95 % ) and monkey chimpanzee, canine and bovine (100 %).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide selected from the hinge region of human MT1-MMP (KLH).

Type of Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Approved: IHC, IHC-P (1:100), WB (2 μg/mL)

Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 2 μg/mL. Immunohistochemistry (paraffin): 1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-glycine,  pH 7.4, 150 mM sodium chloride, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.

Target Details for MMP14

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Alternative Name: MMP14 / MMP-14

Background: Name/Gene ID: MMP14
Subfamily: Metallopeptidase M10A
Family: Protease

Synonyms: MMP14, Membrane type-1 MMP, MT1-MMP, MT1MMP, MT-MMP, MT-MMP 1, Matrix metalloproteinase-14, MMP-14, MMP-X1, MTMMP1

Gene ID: 4323

UniProt: P50281

Pathways: Autophagy