ITGAL antibody (Biotin)

Catalog No. ABIN609922

This Mouse Monoclonal antibody specifically detects ITGAL in FACS, WB and Func. It exhibits reactivity toward Human.

Quick Overview for ITGAL antibody (Biotin) (ABIN609922)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAL antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Western Blotting (WB), Functional Studies (Func)

Clone: 38

Product Details anti-ITGAL Antibody (Biotin)

Specificity: I domain of the integrin alpha L subunit (CD11a) of about 180 kd.

Purification: Protein A purified

Immunogen: Human monocytes.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo, Func, WB

Usage: Function: Blocks binding of ICAM-1 and ICAM-3 to LFA-1 at 5-10 μg/mL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: LFA-1 / CD11A

Background: Name/Gene ID: ITGAL
Family: Integrin

Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A

Gene ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex