ITGAL antibody (PE)

Catalog No. ABIN609924

The PE-conjugated Mouse Monoclonal anti-ITGAL antibody (Clone 38) (ABIN609924) specifically detects ITGAL in FACS, WB and Func. The antibody is reactive with Human samples.

Quick Overview for ITGAL antibody (PE) (ABIN609924)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAL antibody is conjugated to PE

Application: Flow Cytometry (FACS), Western Blotting (WB), Functional Studies (Func)

Clone: 38

Product Details anti-ITGAL Antibody (PE)

Specificity: I domain of the integrin alpha L subunit (CD11a) of about 180 kd.

Purification: Gel filtration

Immunogen: Human monocytes.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo, Func, WB

Usage: Function: Blocks binding of ICAM-1 and ICAM-3 to LFA-1 at 5-10 μg/mL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.3 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: LFA-1 / CD11A

Background: Name/Gene ID: ITGAL
Family: Integrin

Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A

Gene ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex