Fc gamma RII (CD32) antibody (PE)

Catalog No. ABIN610035

This anti- antibody is a Mouse Monoclonal antibody detecting in FACS and Func. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for Fc gamma RII (CD32) antibody (PE) (ABIN610035)

Target: Fc gamma RII (CD32)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 7-3

Product Details

Specificity: Domain 2 epitope of all CD32 isoforms. It exhibits preferential binding to Fc gRIIb (inhibitory) isoform transfectants.

Purification: Gel filtration

Immunogen: Human K562 tumor cells and L cells transfected with human Fc gamma RII.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo, Func

Usage: Function: Intact and F(ab')2 7.3 antibody blocks immune complex binding. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

References

Cho, Klemke: "Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold." in: The Journal of cell biology, Vol. 156, Issue 4, pp. 725-36, (2002) (PubMed).

Target Details

Target: Fc gamma RII (CD32)

Alternative Name: FCGR2 / CD32