Fc gamma RII (CD32) antibody

Catalog No. ABIN610036

This Mouse Monoclonal antibody specifically detects in FACS and Func. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Fc gamma RII (CD32) antibody (ABIN610036)

Target: Fc gamma RII (CD32)

Fragment: F(ab')2 fragment

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 7-3

Product Details

Specificity: Domain 2 epitope of all CD32 isoforms. It exhibits preferential binding to Fc gRIIb (inhibitory) isoform transfectants.

Purification: Gel filtration

Sterility: Sterile filtered

Immunogen: Human K562 tumor cells and L cells transfected with human Fc gamma RII.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: Flo, Func

Usage: Function: Intact and F(ab')2 7.3 antibody blocks immune complex binding. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride. Product was sterile filtered, vialed under aseptic conditions. No preservative added

Preservative: Without preservative

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References

Cho, Klemke: "Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold." in: The Journal of cell biology, Vol. 156, Issue 4, pp. 725-36, (2002) (PubMed).

Target Details

Target: Fc gamma RII (CD32)

Alternative Name: FCGR2 / CD32