CD40 antibody

Catalog No. ABIN610074

This anti-CD40 antibody is a Mouse Monoclonal antibody detecting CD40 in FACS, ELISA, IP and Func. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for CD40 antibody (ABIN610074)

Target: CD40

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD40 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Functional Studies (Func)

Clone: BE-1

Product Details anti-CD40 Antibody

Specificity: CD40 Molecule of about 44 kd.

Purification: Protein A purified

Immunogen: Murine L cells transfectants expressing human CD40.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo, Func, IP

Usage: Function: Binding of cross linked BE-1 will partially activate B cells.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-CD40 antibody (ABIN610074)

Raabe, Rapp: "KSR--a regulator and scaffold protein of the MAPK pathway." in: Science's STKE : signal transduction knowledge environment, Vol. 2002, Issue 136, pp. pe28, (2002) (PubMed).

Storm, Cleveland, Rapp: "Expression of raf family proto-oncogenes in normal mouse tissues." in: Oncogene, Vol. 5, Issue 3, pp. 345-51, (1990) (PubMed).

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background: Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

Gene ID: 958

UniProt: P25942

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints