L-Selectin antibody

Catalog No. ABIN610253

The Mouse Monoclonal anti-L-Selectin antibody has been validated for FACS and Func. It is suitable to detect L-Selectin in samples from Human. There are 2+ publications available.

Quick Overview for L-Selectin antibody (ABIN610253)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This L-Selectin antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: LAM1-116

Product Details anti-L-Selectin Antibody

Specificity: Lectin binding domain of human, mouse, rat and guinea pig CD62L.

Purification: Protein A purified

Immunogen: Mouse pre-B cells expressing human L-selectin.

Type of Immunogen: Cells

Isotype: IgG2a kappa

Application Details

Application Notes: Approved: Flo, Func

Usage: Function: Blocks CD62L function and induces expression of beta-1 and beta-2 integrins. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Preservative: Azide free

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References for anti-L-Selectin antibody (ABIN610253)

Mary, Charrasse, Meriane, Comunale, Travo, Blangy, Gauthier-Rouvière: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).

Merritt, Berika, Zhai, Kirk, Ji, Hardman, Garrod: "Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5846-58, (2002) (PubMed).

Target Details for L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Alternative Name: SELL / L-Selectin / CD62L

Target Type: Chemical

Background: Name/Gene ID: SELL

Synonyms: SELL, CD62L, CD62L antigen, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Lyam-1, LSEL, gp90-MEL, HLHRc, PLNHR, L-selectin, Leu-8, Selectin L, LNHR, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, TQ1, Pln homing receptor

Gene ID: 6402