BAFF antibody

Catalog No. ABIN610263

Cited in 2+ publications. The Mouse Monoclonal anti-BAFF antibody (Clone ANC2H3) (ABIN610263) specifically detects BAFF in ELISA and Func. The antibody is reactive with Human samples.

Quick Overview for BAFF antibody (ABIN610263)

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAFF antibody is un-conjugated

Application: ELISA, Functional Studies (Func)

Clone: ANC2H3

Product Details anti-BAFF Antibody

Specificity: CD257(BAFF) in EIA and blocks binding of recombinant CD257(BAFF)-muCD8 to receptors on Raji cell surface in Flow cytometry.

Purification: Protein A purified

Immunogen: Recombinant soluble human CD257(BAFF).

Type of Immunogen: Recombinant protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA, Func

Usage: Function: Blocks binding of Recombinant CD257(BAFF) to Raji cell surface.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-BAFF antibody (ABIN610263)

Kessels, Engqvist-Goldstein, Drubin: "Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation." in: Molecular biology of the cell, Vol. 11, Issue 1, pp. 393-412, (2000) (PubMed).

Cook, Urrutia, McNiven: "Identification of dynamin 2, an isoform ubiquitously expressed in rat tissues." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 2, pp. 644-8, (1994) (PubMed).

Target Details for BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Alternative Name: BAFF

Background: Name/Gene ID: TNFSF13B
Family: TNF

Synonyms: TNFSF13B, B-cell-activating factor, BAFF, ApoL related ligand TALL-1, B-lymphocyte stimulator, CD257, BLYS, Delta4 BAFF, Delta BAFF, TALL-1, TALL1, ZTNF4, THANK, B lymphocyte stimulator, CD257 antigen, TNFSF20

Gene ID: 10673

UniProt: Q9Y275

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response