MMP20 antibody (AA 108-310)

Catalog No. ABIN6134051

The Rabbit Polyclonal anti-MMP20 antibody has been validated for WB. It is suitable to detect MMP20 in samples from Human.

Quick Overview for MMP20 antibody (AA 108-310) (ABIN6134051)

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP20 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP20 Antibody

Binding Specificity: AA 108-310

Sequence: YRLFPGEPKW KKNTLTYRIS KYTPSMSSVE VDKAVEMALQ AWSSAVPLSF VRINSGEADI MISFENGDHG DSYPFDGPRG TLAHAFAPGE GLGGDTHFDN AEKWTMGTNG FNLFTVAAHE FGHALGLAHS TDPSALMYPT YKYKNPYGFH LPKDDVKGIQ ALYGPRKVFL GKPTLPHAPH HKPSIPDLCD SSSSFDAVTM LGK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 108-310 of human MMP20 (NP_004762.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MMP20

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Alternative Name: MMP20

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.,MMP20,AI2A2,MMP-20,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP20

Molecular Weight: 54 kDa

Gene ID: 9313

UniProt: O60882