RPS6KA1 antibody (pSer380)

Catalog No. ABIN6136172

The Rabbit Polyclonal anti-RPS6KA1 antibody has been validated for WB and IP. It is suitable to detect RPS6KA1 in samples from Human.

Quick Overview for RPS6KA1 antibody (pSer380) (ABIN6136172)

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RPS6KA1 Antibody

Binding Specificity: pSer380

Sequence: GFSFV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Immunogen: A synthetic phosphorylated peptide around S380 of human p90Rsk/RSK1/RPS6KA1 (NP_002944.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RPS6KA1

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Alternative Name: RPS6KA1

Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,HU-1,MAPKAPK1A,RSK,RSK1,p90Rsk,RPS6KA1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,mTOR Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Cycle,G2/M DNA Damage Checkpoint,Microtubules,Immunology & Inflammation,NF-kB Signaling Pathway,Neuroscience,Protein phosphorylation,RPS6KA1

Molecular Weight: 72 kDa/81 kDa/82 kDa/83 kDa

Gene ID: 6195

UniProt: Q15418

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades