A1CF antibody (AA 50-120)

Catalog No. ABIN6136302

The Rabbit Polyclonal anti-A1CF antibody has been validated for WB and IHC. It is suitable to detect A1CF in samples from Human.

Quick Overview for A1CF antibody (AA 50-120) (ABIN6136302)

Target: A1CF (APOBEC1 Complementation Factor (A1CF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This A1CF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-A1CF Antibody

Binding Specificity: AA 50-120

Sequence: APPERGCEIF IGKLPRDLFE DELIPLCEKI GKIYEMRMMM DFNGNNRGYA FVTFSNKVEA KNAIKQLNNY E

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-120 of human A1CF (NP_055391.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for A1CF

Target: A1CF (APOBEC1 Complementation Factor (A1CF))

Alternative Name: A1CF

Background: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.,A1CF,ACF,ACF64,ACF65,APOBEC1CF,ASP,Epigenetics & Nuclear Signaling,A1CF

Molecular Weight: 55 kDa/58 kDa/62 kDa/64 kDa/65 kDa

Gene ID: 29974

UniProt: Q9NQ94