CXCR7 antibody (AA 50-150)

Catalog No. ABIN6136434

The Rabbit Polyclonal anti-CXCR7 antibody has been validated for WB and IF. It is suitable to detect CXCR7 in samples from Human.

Quick Overview for CXCR7 antibody (AA 50-150) (ABIN6136434)

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CXCR7 Antibody

Binding Specificity: AA 50-150

Sequence: IYIFIFVIGM IANSVVVWVN IQAKTTGYDT HCYILNLAIA DLWVVLTIPV WVVSLVQHNQ WPMGELTCKV THLIFSINLF GSIFFLTCMS VDRYLSITYF T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACKR3 (NP_064707.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CXCR7

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Alternative Name: ACKR3

Background: This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.,ACKR3,CMKOR1,CXC-R7,CXCR-7,CXCR7,GPR159,RDC-1,RDC1,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),ACKR3

Molecular Weight: 41 kDa

Gene ID: 57007

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling