ADAM19 antibody (AA 203-460)

Catalog No. ABIN6136525

The Rabbit Polyclonal anti-ADAM19 antibody has been validated for WB and IF. It is suitable to detect ADAM19 in samples from Human.

Quick Overview for ADAM19 antibody (AA 203-460) (ABIN6136525)

Target: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM19 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ADAM19 Antibody

Binding Specificity: AA 203-460

Sequence: REDLNSMKYV ELYLVADYLE FQKNRRDQDA TKHKLIEIAN YVDKFYRSLN IRIALVGLEV WTHGNMCEVS ENPYSTLWSF LSWRRKLLAQ KYHDNAQLIT GMSFHGTTIG LAPLMAMCSV YQSGGVNMDH SENAIGVAAT MAHEMGHNFG MTHDSADCCS ASAADGGCIM AAATGHPFPK VFNGCNRREL DRYLQSGGGM CLSNMPDTRM LYGGRRCGNG YLEDGEECDC GEEEECNNPC CNASNCTLRP GAECAHGS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 203-460 of human ADAM19 (NP_150377.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADAM19

Target: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Alternative Name: ADAM19

Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease.,ADAM19,FKSG34,MADDAM,MLTNB,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,ADAM19

Molecular Weight: 100 kDa/104 kDa

Gene ID: 8728

UniProt: Q9H013