AGL antibody (AA 1233-1532)

Catalog No. ABIN6136632

This Rabbit Polyclonal antibody specifically detects AGL in WB. It exhibits reactivity toward Human.

Quick Overview for AGL antibody (AA 1233-1532) (ABIN6136632)

Target: AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AGL Antibody

Binding Specificity: AA 1233-1532

Sequence: EGFNITAGVD EETGFVYGGN RFNCGTWMDK MGESDRARNR GIPATPRDGS AVEIVGLSKS AVRWLLELSK KNIFPYHEVT VKRHGKAIKV SYDEWNRKIQ DNFEKLFHVS EDPSDLNEKH PNLVHKRGIY KDSYGASSPW CDYQLRPNFT IAMVVAPELF TTEKAWKALE IAEKKLLGPL GMKTLDPDDM VYCGIYDNAL DNDNYNLAKG FNYHQGPEWL WPIGYFLRAK LYFSRLMGPE TTAKTIVLVK NVLSRHYVHL ERSPWKGLPE LTNENAQYCP FSCETQAWSI ATILETLYDL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1233-1532 of human AGL (NP_000633.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AGL

Target: AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))

Alternative Name: AGL

Background: This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.,AGL,GDE,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,AGL

Molecular Weight: 172 kDa/174 kDa

Gene ID: 178

UniProt: P35573

Pathways: Cellular Glucan Metabolic Process