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AGL antibody (C-Term)

AGL Reactivity: Human WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357688
  • Target See all AGL Antibodies
    AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))
    Binding Specificity
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    AA 1487-1516, C-Term
    Reactivity
    • 39
    • 1
    Human
    Host
    • 37
    • 2
    Rabbit
    Clonality
    • 38
    • 1
    Polyclonal
    Conjugate
    • 15
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AGL antibody is un-conjugated
    Application
    • 23
    • 23
    • 22
    • 10
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody is specific to AGL/GDE (C-term).
    Purification
    Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    KLH conjugated synthetic peptide between 1487~1516 amino acids from the C-terminal region of Human AGL
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AGL Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western Blot: 1/100-1/500. This antibody is reported to work in Immunofluorescence (See: Cheng, Alan, et al. Genes &Dev.2007 Oct 01,21(19): 2399-2409).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))
    Alternative Name
    AGL / GDE (AGL Products)
    Synonyms
    DDBDRAFT_0219237 antibody, DDBDRAFT_0234114 antibody, DDB_0219237 antibody, DDB_0234114 antibody, GDE antibody, 1110061O17Rik antibody, 9430004C13Rik antibody, 9630046L06Rik antibody, AI850929 antibody, C77197 antibody, amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase antibody, glycogen debranching enzyme antibody, glycogen debranching protein antibody, amylo-1,6-glucosidase, 4-alpha-glucanotransferase antibody, AGL antibody, agl antibody, MMAH_RS03870 antibody, Agl antibody
    Background
    AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.Synonyms: 4-alpha-glucanotransferase, 6-glucosidase, Amylo-alpha-1, Glycogen debranching enzyme
    Molecular Weight
    174764 Da
    Gene ID
    178, 9606
    UniProt
    P35573
    Pathways
    Cellular Glucan Metabolic Process
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